Department of Medicine
Faculty Profiles by Division

Department of Medicine

Faculty Profiles

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photo Gerard Apodaca, PhD

Renal-Electrolyte

Professor of Cell Biology & Physiology

Email: gla6@pitt.edu

Phone: 412-383-8893

Contact
Office: 980 Scaife Hall
3550 Terrace St.
Pittsburgh, PA 15261
 
Phone: 412-383-8893
Fax: 412-383-8955
E-mail: gla6@pitt.edu
Education and Training
Education
B.A. in Biology, Rollins College, Winter Park, FL., 1983
Ph.D. in Experimental Pathology, University of California, San Francisco, CA, 1989
Training
Postdoctoral Fellow, University of California, San Francisco, CA., 1995
Research Interest
Dr. Apodaca’s lab studies the biology of the epithelial cells that line the inner surface of the bladder and ureters (urothelium), as well the cells that line the tubules that comprise the kidney nephron. Dr. Apodaca’s lab has three major projects in the laboratory: 1) Studies of stretch-regulated membrane traffic in umbrella cells. 2) Analysis of tight junction morphology and function in response to stretch. 3) Exploration of what the role is of uroplakins in urinary tract development and congenital anaomalies of the kidney and urinary tract.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Gallo LI, Liao Y, Ruiz WG, Clayton DR, Li M, Liu YJ, Jiang Y, Fukuda M, Apodaca G, Yin XM. TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells. Molecular Biology of the Cell. 2014; 25(23): 3779-97.
Sponsored Research/Activities
Title: REGULATION OF RENAL PILVIC CONTRACTIONS ROLE OF THE UROTHELIUM
Role: Principal Investigator
Funding Agency: Dialysis Clinic, Inc.
Grant Number: RES
Start Year: 2020
End Year: 2021
Title: Role of Piezo Channels in Bladder Function and Dysfunction
Role: Co-Principal Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01
Start Year: 2019
End Year: 2024
Title: Bladder Mucosal Dysfunction During Aging
Role: Co-Principal Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG056944
Start Year: 2018
End Year: 2023
Title: Pittsburgh Center for Kidney Research - Core C
Role: Core Leader
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: P30 DK079307
Start Year: 2018
End Year: 2023
Notable Achievements
Established Investigator Award, AHA, 2003
MERIT Award, NIH, 2004
Member ACS Cell Structure and Metastasis Study Section, 2005
Appointed UPSOM Academy of Master Educators, 2006
William E. Brown MSTP Mentor of the Year Award, 2007
Member NIH Membrane Biology and Protein Processing Study Section, 2012
Associate Editor, American Journal of Physiology, Renal Physiology, 2007
Editor, Section in Membrane Traffic, Frontiers in Cell and Developmental Biology, 2013
American Society of Cell Biology, 1993
American Physiological Society, 2002