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Department of Medicine

Department of Medicine

  Division of Gastroenterology, Hepatology and Nutrition

T32 Research Training

Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32): 
BIG DATA and PRECISION MEDICINE

The Division of Gastroenterology, Hepatology and Nutrition has managed a successful T32 training grant with research trainees for the past ten years.  Based on the translational research strengths of the Division and its commitment to complex disease interactions and treatments, the focus of the Division’s T32 program centers on big data and precision medicine in gastroenterology and hepatology.

Training young physicians and scientists for future success with patient-centered solutions requires an innovative training program within a supportive environment.  New opportunities and national health care trends inspired our UPMC leadership to create a forward-thinking T32 initiative designed to attract and retain top-quality trainees and to equip a new generation of physicians and scientists. 

With the structure of the Division’s successful U01 programs, our T32 trainees will integrate the tools of big data and personalized medicine into clinical and translational research and team teaching.  This novel program is designed to:

The T32 trainee’s research plan includes an experienced program director and four co-directors who are leaders in clinical-translational research, basic sciences, biomedical informatics, and computational biology. Trainees will receive intense classroom and practical training through the University of Pittsburgh’s Institute for Clinical Research Education (ICRE), followed by core classes and electives in basic, translational, and/or clinical sciences.  

Each trainee will work with a mentoring team comprised of a physician, scientists, and a domain expert in big data, who will work with the trainee to develop an individual development plan to ensure compliance with the following:

Big Data electives are built into each trainee’s individual development plan (i.e., Foundations of Translational Bioinformatics, Symbolic Methods in Artificial Intelligence, Probabilistic Methods for Computer-Based Decision Support, Machine Learning, Computational Genomics, and Laboratory Methods for Computational Biologists).  Additional experience may be gain through participation in existing U01s, multicenter clinical/translational studies, and internships.

There is no precedent for this program—despite a clear need. However, our Division’s ongoing training success demonstrates T32 success and highlights outstanding faculty and a nurturing and energetic environment.   

Co-Program Directors:

David C. Whitcomb, MD, PhD                    
Giant Eagle Foundation Professor of Human Genetics
Professor of Medicine, Cell Biology & Physiology and Human Genetics
Director, Pancreas Center

David G. Binion, MD
Professor of Medicine
Director, Nutrition Support
Co-Director & Translational Research Head, IBD Center

For more information: