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Department of Medicine

Department of Medicine

  Division of Pulmonary, Allergy and Critical Care Medicine



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photo Bryan J. McVerry, MD

Associate Professor of Medicine

Assistant Professor of Environmental and Occupational Health

Director, Pulmonary and Critical Care Medicine Fellowship Program

Associate Director, UPMC Presbyterian Medical Intensive Care Unit

Director, Translational Research in Acute Lung Injury

Email: mcverrybj@upmc.edu

Phone: 412-648-3098

Contact
Office: UPMC Montefiore Hospital, NW628
3459 Fifth Avenue
Pittsburgh, PA 15213
 
Phone: 412-648-3098
Fax: 412-383-7113
E-mail: mcverrybj@upmc.edu
Administrative Assistant:
Stacie Truszkowski
Email: truszkowskisl@upmc.edu
Phone: 412-648-3098
Fax: 412-383-7113
Education and Training
Education
BS, Lehigh University, 1992
MD, Georgetown University, 1997
Training
Residency, Internal Medicine, University of Chicago Hospital, 2000
Post-Doctoral Research Fellowship, Emergency Medicine, University of Chicago, Pritzker School of Medicine, 2001
Post-Doctoral Clinical and Research Fellowship, Pulmonary and Critical Care, Johns Hopkins University School of Medicine, 2005
Research Interest
Dr. McVerry’s research interest is focused on basic and translational investigation of the biological mechanisms underlying the development and consequences of sepsis and acute lung injury. His research efforts are designed to span the continuum from the bench to the bedside.
Clinical Interest
Dr. McVerry’s clinical interest and expertise focuses on the care of critically ill patients in the medical ICU, specifically those with acute lung injury and ARDS. He has additional interest in early implementation of physical rehabilitation in critically ill patients, in minimizing sedation to facilitate physical rehabilitation in mechanically ventilated patients, in endocrine dysregulation in critical illness, and in quality improvement in the Medical ICU.
Educational Interest
Dr. McVerry's educational interest focuses on the development of academic physicians as clinicians, educators, and scientists.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Singamsetty, S, Shah, FA, Guo, L, Watanabe, Y, McDonald, SA, Sharma, R, Zhang, Y, Alonso, LC, O'Donnell, CP, McVerry, BJ. Early Initiation of Low-Level Parenteral Dextrose Induces an Accelerated Diabetic Phenotype in Septic C57BL/6J Mice. Appl Physiol Nutr Metabol. 2016; 41(1): 12-19.
Wu, F, Szczepaniak, WS, Shiva, S, Liu, H, Wang, Y, Wang, L, Kelley, EE, Chen, AF, Gladwin, MT, McVerry, BJ. Nox2-dependent glutathionylation of endothelial NOS leads to uncoupled superoxide production and endothelial barrier dysfunction in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2014; Dec 15; 307(12): L987-97.
Watanabe, Y, Singamsetty, S, Zou, B, Guo, L, Stefanovski, D, Alonso, LC, Garcia-Ocana, A, O'Donnell, CP, McVerry, BJ. Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice. PLoS One. 2013; Jun24;8(6): e67716.
Chen, BB, Coon, TA, Glasser, JR, McVerry, BJ, Zhao, J, Zhao, Y, Zou, C, Ellis, B, Zhang, Y, Mallampalli, RK. A combinatorial F box protein directed pathway controls TRAF stability to regulate inflammation. Nat Immunol. 2013; May; 14(5): 470-9.
Ray, NB, Durairaj, L, Chen, BB, McVerry, BJ, Ryan, AJ, Donahoe, MD, Agassandian, M, Hayes-Rowan, E, Coon, TA, Butler, PL, Gakhar, L, Mathur SN, Sieren, JC, Tyurina, YY, Kagan, VE, McLennan, G, Mallampalli, RK. Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia. Nat Med. 2010; Oct;16(10): 1120-7.
Szczepaniak, WS, Pitt, BR, McVerry, BJ. S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate. Am J Physiol Lung Cell Mol Physiol. 2010; Jul;299(1): L137-45.
McVerry, BJ, Peng, X, Hassoun, PM, Sammani, S, Simon, BA, Garcia, JG. Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. Am J Respir Crit Care Med. 2004; Nov 1; 170(9): 987-93.
Sponsored Research/Activities
Title: Combination of Extracorporeal Life Support and Mesenchymal Stem Cell Therapy for Treatment of ARDS in Combat Casualties and Evacuation of Service Members with ARDS
Role: Co-Investigator
Funding Agency: Army
Start Year: 2015
End Year: 2017
Title: Cardiolipin as a Novel Mediator of Acute Lung Injury - Core C
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: P01 HL114453
Start Year: 2014
End Year: 2018
Title: Antidote for Inhaled CO Poisoning Based on Mutationally Engineered Neuroglobin
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL125886
Start Year: 2014
End Year: 2018
Title: Mechanisms of Lung Homeostatis by F box Proteins
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL097376
Start Year: 2014
End Year: 2018
Title: RV/PA Recoupling by Bone Marrow Derived Mesenchymal Stem Cells
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL114795
Start Year: 2012
End Year: 2017
Title: Pulmonary Vascular Dysfunction in Acute Lung Injury: The Role of Oxidative Stress
Role: Co-Investigator
Funding Agency: American Heart Association-National
Start Year: 2012
End Year: 2014
Notable Achievements
Alpha Omega Alpha, Georgetown University School Medicine, 1996
Resuscitation Science Research Fellowship, Univ of Chicago Dept of Medicine, 2000-2001
Individual Ruth L. Kirschstein National Research Service Award (F32), 2004-2005
Ironman Triathalon Finisher, 2004 & 2008
NIH Mentored Clinical Scientist Research Career Development Award (K08), 2007-2012
Conferral of Tenure, 2017