Department of Medicine

University of Pittsburgh

Division of Infectious Diseases

Office of the Division Chief
John W. Mellors, MD
3550 Terrace Street
Scaife Hall-Suite 818
Pittsburgh, PA 15261
Phone: 412-383-7963
Fax: 412-383-7982
Email: jwm1@pitt.edu
Assistant: Lois Mathews
Email: lmm112@pitt.edu

ID Administrative Offices
c/o Division Administrator
Lisa Gundel
3601 Fifth Avenue
Falk Medical Building
Suite 3A - Room 303
Pittsburgh, PA 15213-2582
Phone: 412-648-6593
Fax: 412-648-6399
Email: lgundel@mail.magee.edu
Assistant: Betty Edwards
Email: eae5@pitt.edu
Phone: 412-648-6273

PATIENT SCHEDULING
General Infectious Diseases Clinic
University of Pittsburgh Infectious Diseases Clinics
Falk Medical Building
3601 Fifth Avenue – 7th Floor Falk Medical Building
Pittsburgh, PA 15213
Appointments: 412-647-0996
Main ID Fax Number: 412-647-3162

HIV/AIDS Care Center
University of Pittsburgh Infectious Diseases
Falk Medical Building
3601 Fifth Avenue – 7th Floor Falk Medical Building
Pittsburgh, PA 15213

Pittsburgh AIDS Center for Treatment Clinic (PACT)
PACT Appointments: 412-647-7228 or 1-877-788-7228
PACT Fax Number: 412-647-7951

Pittsburgh Treatment and Evaluation Unit (PTEU)
PTEU Appointments: 412-647-8125 or 1-888-396-7838
PTEU Fax Number: 412-647-6253

Transplant Infectious Diseases Clinic
University of Pittsburgh Infectious Diseases Clinics
Falk Medical Building
3601 Fifth Avenue – 7th Floor Falk Medical Building
Pittsburgh, PA 15213
Appointments: 412-647-0996
ID Fax Number: 412-647-3162

ID Fellowship Coordinator
Kim Barnhart
University of Pittsburgh Infectious Diseases Clinics
Falk Medical Building
3601 Fifth Avenue – Suite 3A
Pittsburgh, PA 15213
Phone: 412-648-6406
Fax: 412-648-6399
Email: kib9@pitt.edu

Shaoji Cheng, MD

photo
Office: 3550 Terrace Street, Scaife S869
Pittsburgh, PA 15261
 
Phone: 412-648-9928
E-mail: chengs@dom.pitt.edu

Education
M.D., Bangbu Medical College, 1985
Ph.D., Beijing TB & Thoracic Tumor Institute, 1995

Training
Post-doctor, The Johns Hopkins University, 1998
Post-doctor, University of Florida, 1999
Assistant Scientist, University of Florida, 2007

Area of Specialization/Research Interest  
Pathogenesis of fungal infection
Antibody response of fungal infection
 

Profile
Shaoji Cheng completed his undergraduate education at Bangbu Medical College, China, and received his Ph.D. degree from Beijing TB & Thoracic Tumor Institute, China. He completed post-doctor training in the Johns Hopkins University and the Univesity of Florida. He is currently Research Associate Professor at the University of Pittsburgh. His main research interest is molecular pathogenesis of Candida infection. He is currently focusing on identifying candidal virulence factors.

Recent Peer-Reviewed Publications
Title: Candida albicans RFX2 encodes a DNA binding protein involved in DNA damage responses, morphogenesis and virulence
Author(s): Binghua Hao, Cornelius J Clancy, Shaoji Cheng, Suresh B Raman, Kenneth Iczkowski, M. Hong Nguyen
Year: 2009
Journal: Eukaryotic Cell
Volume: 8(4)
Page(s): 627-39
Title: The Candida albicans phosphatase Inp51p interacts with the EH protein Irs4p and regulates phosphatidylinositol-4-5-bisphosphate levels, the cell integrity pathway, and virulence
Author(s): H. Badrane, M. H. Nguyen, S. Cheng, V. Kumar, H. Derendorf, K. A. Iczkowski, C. J. Clancy
Year: 2008
Journal: Microbiology
Volume: 154(11)
Page(s): 3296-308
Title: IgG responses against a panel of Candida albicans antigens are accurate and early markers for systemic candidiasis
Author(s): Cornelius J. Clancy, Minh-Ly Nguyen, Shaoji Cheng, Hong Huang, Guixiang Fan, Reia A. Jaber, John R. Wingard, Christina Cline, M. Hong Nguyen
Year: 2008
Journal: J. Clin. Microbiol.
Volume: 46(5)
Page(s): 1647-1654
Title: Uncoupling of Oxidative Phosphorylation Enables Candida albicans to Resist Killing by Phagocytes and Persist in Tissue
Author(s): Shaoji Cheng, Cornelius J. Clancy, Zongde Zhang, Binghua Hao, Wei Wang, Kenneth A. Iczkowski, Michael A. Pfaller, M. Hong Nguyen
Year: 2007
Journal: Cellular Microbiology
Volume: 9
Page(s): 492-501
Title: A Candida albicans petite mutant strain with uncoupled oxidative phosphorylation overexpresses MDR1 and has diminished susceptibility to fluconazole and voriconazole
Author(s): Shaoji Cheng, Cornelius J Clancy, Katherine T. Nguyen, William Clapp, M. Hong Nguyen
Year: 2007
Journal: Antimicrobial Agents and Chemotherapy
Volume: 51(5)
Page(s): 1855-1858
Title: Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis
Author(s): Suresh Babu Raman, M. Hong Nguyen, Zongde Zhang, Shaoji Cheng, Hong Yan Jia, Nghe Weisner, Kenneth Iczkowski, Cornelius J. Clancy
Year: 2006
Journal: Molecular Microbiology
Volume: 60
Page(s): 697-709
Title: The role of Candida albicans NOT5 in virulence depends upon diverse host factors in vivo.
Author(s): Shaoji Cheng, Cornelius J Clancy, Mary Ann Checkley, Zongde Zhang, Karen L Wozniak, Kalpathi R. Seshan, Hong Yan Jia, Paul Fidel, Garry Cole
Year: 2005
Journal: Infection and Immunity
Volume: 73
Page(s): 6101-6103
Title: Candida albicans IRS4 contributes to hyphal formation and virulence after the initial stages of disseminated candidiasis
Author(s): Hassan Badrane, Shaoji Cheng, M. Hong Nguyen, Hong Yan Jia, Zongde Zhang, Nghe Weisner, Cornelius J. Clancy
Year: 2005
Journal: Microbiology
Volume: 151
Page(s): 2923-2931
Title: Assessment of Candida albicans genes induced during infections as a tool to understand pathogenesis
Author(s): M. Hong Nguyen, Shaoji Cheng, Cornelius J. Clancy
Year: 2004
Journal: Med Mycol
Volume: 42(4)
Page(s): 293-304
Title: Identification of Candida albicans genes induced during thrush offers insight into pathogenesis Molecular Microbiology.2003, 48:1275-1288
Author(s): Shaoji Cheng, Cornelius J. Clancy, Mary Ann Checkley, Martin Handfield, Jeffrey D. Hillman, Ann Progulske-Fox, Alfred S. Lewin, Paul L. Fidel, M. Hong Nguyen
Year: 2003
Journal: Molecular Microbiology
Volume: 48
Page(s): 1275-1288