Department of Medicine

University of Pittsburgh

Division of Infectious Diseases

Office of the Division Chief
John W. Mellors, MD
3550 Terrace Street
Scaife Hall-Suite 818
Pittsburgh, PA 15261
Phone: 412-383-7963
Fax: 412-383-7982
Email: jwm1@pitt.edu
Assistant: Lois Mathews
Email: lmm112@pitt.edu

ID Administrative Offices
c/o Division Administrator
Lisa Gundel
3601 Fifth Avenue
Falk Medical Building
Suite 3A - Room 303
Pittsburgh, PA 15213-2582
Phone: 412-648-6593
Fax: 412-648-6399
Email: lgundel@mail.magee.edu
Assistant: Betty Edwards
Email: eae5@pitt.edu
Phone: 412-648-6273

PATIENT SCHEDULING
General Infectious Diseases Clinic
University of Pittsburgh Infectious Diseases Clinics
Falk Medical Building
3601 Fifth Avenue – 7th Floor Falk Medical Building
Pittsburgh, PA 15213
Appointments: 412-647-0996
Main ID Fax Number: 412-647-3162

HIV/AIDS Care Center
University of Pittsburgh Infectious Diseases
Falk Medical Building
3601 Fifth Avenue – 7th Floor Falk Medical Building
Pittsburgh, PA 15213

Pittsburgh AIDS Center for Treatment Clinic (PACT)
PACT Appointments: 412-647-7228 or 1-877-788-7228
PACT Fax Number: 412-647-7951

Pittsburgh Treatment and Evaluation Unit (PTEU)
PTEU Appointments: 412-647-8125 or 1-888-396-7838
PTEU Fax Number: 412-647-6253

Transplant Infectious Diseases Clinic
University of Pittsburgh Infectious Diseases Clinics
Falk Medical Building
3601 Fifth Avenue – 7th Floor Falk Medical Building
Pittsburgh, PA 15213
Appointments: 412-647-0996
ID Fax Number: 412-647-3162

ID Fellowship Coordinator
Kim Barnhart
University of Pittsburgh Infectious Diseases Clinics
Falk Medical Building
3601 Fifth Avenue – Suite 3A
Pittsburgh, PA 15213
Phone: 412-648-6406
Fax: 412-648-6399
Email: kib9@pitt.edu

Zandrea Ambrose, PhD
photo

Assistant Professor of Medicine, Division of Infectious Diseases

Research Affiliate, Washington National Primate Research Center
Office: 817B Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
 
Phone: 412-624-0512
Fax: 412-648-8521
E-mail: zaa4@pitt.edu
Education
B.A., Ohio Wesleyan University, 1994
Ph.D., University of Washington, 2001
Training
Research fellow, HIV Drug Resistance Program, National Cancer Institute, 2007
Area of Specialization/Research Interest  
Identification and eradication of HIV reservoirs
Understanding the evolution of HIV drug resistance
Mechanisms of action of novel antiretroviral drugs
Understanding the early infection pathway of HIV-1
 
Lab Personnel and Web page
Jean Ndjomou, PhD; Tamera Kirkland; James Matous
Recent Peer-Reviewed Publications
Title: A macaque model of HIV-1 infection
Author(s): Hatziioannou T, Ambrose Z, Chung NPY, Piatak M, Yuan F, Trubey CM, Coalter V, Kiser R, et al.
Year: 2009
Journal: Proceedings of the National Academy of Sciences USA
Volume: 106
Page(s): 4425-4429
Title: The HIV-1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs
Author(s): Ambrose Z., Herman B.D., Sheen C.W., Zelina S., Moore K.L., Tachedjian G., Nissley D.V., Sluis-Cremer N.
Year: 2009
Journal: Journal of Virology
Volume: 82
Page(s): 3826-3833
Title: Of mice and monkeys: new advances in animal models to study HIV-1 therapy and prophylaxis
Author(s): Ambrose Z., KewalRamani V.N.
Year: 2008
Journal: Future HIV Therapy
Volume: 2
Page(s): 363-373
Title: Incomplete protection against SIV vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges
Author(s): Ambrose Z., Compton L., Piatak M., Lu D., Alvord W.G., Lubomirski M.S., Hildreth J.E.K., Lifson J.D., Miller C.J., KewalRamani V.N.
Year: 2008
Journal: Journal of Virology
Volume: 82
Page(s): 6591-6599
Title: HIV/AIDS: in search of an animal model
Author(s): Ambrose Z., KewalRamani V.N., Bieniasz P.D., Hatziioannou T.
Year: 2007
Journal: Trends in Biotechnology
Volume: 25
Page(s): 333-337
Title: Suppression of viremia and evolution of HIV-1 drug resistance in a macaque model for antiretroviral therapy
Author(s): Ambrose Z., Palmer S., Boltz V.F., Kearney M., Larsen K., Polacino P., Flanary L., Oswald K., Piatak M., et al.
Year: 2007
Journal: Journal of Virology
Volume: 81
Page(s): 12145-12155
Title: The nucleoside analogs 4’C-methyl thymidine and 4’C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants
Author(s): Boyer P.L., Julias J.G., Ambrose Z., Siddiqui M.A., Marquez V.E., Hughes S.H.
Year: 2007
Journal: Journal of Molecular Biology
Volume: 371
Page(s): 873-882
Title: The level of reverse transcriptase (RT) in human immunodeficiency virus type 1 particles affects susceptibility to non-nucleoside RT inhibitors but not to lamivudine
Author(s): Ambrose Z., Julias J.G., Boyer P.L., KewalRamani V.N., Hughes S.H.
Year: 2006
Journal: Journal of Virology
Volume: 80
Page(s): 2578-2581
Title: In vitro characterization of an simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques
Author(s): Ambrose Z., Boltz V., Palmer S., Coffin J.M., Hughes S.H., KewalRamani V.N.
Year: 2004
Journal: Journal of Virology
Volume: 78
Page(s): 13553-13561
Title: Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV89.6
Author(s): Ambrose Z., Thompson J., Larsen K., Kuller L., Panicali D.L., Clements J.D., Agy M., Montefiori D.C., Hu S.L., Bosch M.L.
Year: 2003
Journal: Virology
Volume: 308
Page(s): 178-190