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Department of Medicine

Department of Medicine

  Division of General Internal Medicine

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photo Dana L. Tudorascu, PhD

Assistant Professor of Medicine, Biostatistics, Psychiatry and Clinical and Translational Science

Email: dlt30@pitt.edu

Phone: 412-864-3023

Contact
Office: 200 Meyran Ave.
Suite #326
Pittsburgh, PA 15213
 
Phone: 412-864-3023
Fax: 412-586-9673
E-mail: dlt30@pitt.edu
Education and Training
Education
BSc, Mathematics, University of Craiova, Romania, 1999
MSc, Computational Mathematics, Duquesne University, 2003
PhD, Biostatistics, University of Pittsburgh, 2009
Research Interest
Dr. Tudorascu joined the faculty in 2011 as an Assistant Professor of Medicine and Biostatistics. She collaborates with investigators on design and analysis of clinical research projects. Her specific interests are in the analysis of structural MRI, functional MRI (task/resting state/connectivity), and PET data with applications in healthy aging population and patients with Alzheimer's disease. Dr. Tudorascu is also interested in investigating and improving registration and classification methods for individuals with white-matter disease.

In addition to neuroimaging analysis, Dr. Tudorascu is also the lead statistician on two clinical trails: a PCORI trial on spinal stenosis and a weight management trial (MAINTAIN). She received an Honorable Mention in 2014 from the Aging Institute at the University of Pittsburgh for investigating the potential mechanism of resilience to brain aging.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Karim, H.T., Andreescu, C., MacCloud, R.L., Butters, M.A., Reynolds, C.F. 3rd,, Aizenstein, H.J., Tudorascu, D.L. The effects of white matter disease on the accuracy of automated segmentation. Psychiatry Research:Neuroimaging. 2016; 253: 7-14.
Karim, H.T., Andreescu, C., Tudorascu, D., Smagula, S.F., Butters, M.A., Karp, J.F., Reynolds, C., Aizenstein, H.J. Intrinsic functional connectivity in late-life depression: trajectories over the course of pharmacotherapy in remitters and non-remitters. Molecular Psychiatry. 2016.
Yau, W.Y., Tudorascu, D.L., McDade, E.M., Ikonomovic, S., James, J.A., Minhas, D., Mowrey, W., Sheu, L.K., Snitz, B.E., Weissfeld, L., Gianaros, P.J., Aizenstein, H.J., Price, J.C., Mathis, C.A., Lopez, O.L., Klunk, W.E. Longitudinal assessment of neuroimaging and clinical markers in autosomal dominant Alzheimer's disease: a prospective cohort study. Lancet Neurology. 2015; 14(8): 804-813.
Khalaf A, Edelman K, Tudorascu DL, Andreescu C, Reynolds CF, Aizenstein H. White Matter Hyperintensity Accumulation During Treatment of Late-Life Depression. Neuropsychopharmacology. 2015; 253: 7-14.
Andreescu C, Sheu LK, Tudorascu DL, Gross JJ, Walker S, Banihashemi L, Aizenstein HJ. Emotion reactivity and regulation in late-life generalized anxiety disorder: Functional connectivity at baseline and post-treatment. American Journal of Geriatric Psychiatry. 2015; 23: 200-214.
Seppala EM, Nitschke JB, Tudorascu DL, Hayes A, Goldstein MR, Nguyen DT, Perlman D, Davidson RJ. Breathing-based meditation decreases posttraumatic stress disorder symptoms in U.S. military veterans: a randomized controlled longitudinal study. Journal of Traumatic Stress. 2014; 27: 397-405.
Hillmer AT, Tudorascu DL, Wooten DW, Lao PJ, Barnhart TE, Ahlers EO, Resch LM, Larson JA, Converse AK, Moore CF, Schneider ML, Christian BT. Changes in the a4ß2* nicotinic acetylcholine system during chronic controlled alcohol exposure in nonhuman primates. Drug and Alcohol Dependence. 2014; 138: 216-219.
Sponsored Research/Activities
Title: Functional Neuroanatomy Correlates of Worry in Older Adults
Role: Co-Investigator
Funding Agency: National Institute of Mental Health
Grant Number: R01 MH108509
Start Year: 2016
End Year: 2021
Title: High Performance Imaging for Assessment of Small Vessel Disease in Older Adults with Depression
Role: Co-Investigator
Funding Agency: National Institute of Mental Health
Grant Number: R01 MH111265
Start Year: 2016
End Year: 2021
Title: Neural Mechanisms of Monoaminergic Engagement in Late-Life Depression Treatment Response (NEMO)
Role: Co-Investigator
Funding Agency: National Institute of Mental Health
Grant Number: R01 MH076079
Start Year: 2016
End Year: 2021
Title: Immune Airway-Epithelial Interactions in Steroid-Refractory Severe Asthma - Project 1
Role: Co-Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: P01 AI106684
Start Year: 2015
End Year: 2020
Title: In Vivo Characterization of the PET Pharmacokinetic Properties of T807 in Humans
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG050436
Start Year: 2015
End Year: 2018
Title: Amyloid Pathology and Cognition in Normal Elderly
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: RF1 AG025516
Start Year: 2014
End Year: 2019
Title: ADRC - Project 2: Natural History of Amyloid Disposition and Familiar AD
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: P50 AG005133
Start Year: 2014
End Year: 2015
Title: Lumbar Spinal Stenosis
Role: Co-Investigator
Funding Agency: Patient-Centered Outcomes Research Institute
Start Year: 2013
End Year: 2016
Title: Maintaining Activity and Nutrition Through Technology-Assisted Innovation in Primary Care (MAINTAIN-PC)
Role: Co-Investigator
Funding Agency: Agency for Healthcare Research and Quality
Grant Number: R18 HS021162
Start Year: 2012
End Year: 2017
Title: Resilience to Mobility Impairment: Neural Correlates and Protective Factors
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG037451
Start Year: 2012
End Year: 2016
Title: Androgen Signaling in BPH
Role: Co-Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK088793
Start Year: 2010
End Year: 2014
Title: University of Pittsburgh Clinical and Translational Science Institute - Research Education Core
Role: ICRE Faculty
Funding Agency: National Center for Advancing Translational Sciences
Grant Number: UL1 TR000005
Start Year: 2011
End Year: 2016
Title: Mapping of Post-Concussive White Matter Injuries Utilizing Symptom Clusters
Role: Statistician
Funding Agency: National Institute of Biomedical Imaging and Bioengineering
Grant Number: R21 EB017851
Start Year: 2014
End Year: 2016
Title: Pharmacologist MRI Predictors of Treatment Response in Late-Life Depression
Role: Statistician
Funding Agency: Western Psychiatric Institute & Clinic/National Institute of Mental Health
Grant Number: R01 MH076079
Start Year: 2011
End Year: 2016